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Sources:
The roots of Sophora
flauescens Ait. Family Leguminosae.
Constituents:
Containing matrine, oxymatrine, sophoranol, N-methylcyti-
sine, anagyrine, isomatrine, etc.
Actions:The total
alkaloids, matrine and oxymatrine were effective against S180
sarcoma, in which, the single principle of alkaloids its inhibiting
rate was over 35%, the mixed alkaloids C at dose of 113mg/kg*10d
with ip., its inhibiting rate was 61.38%, against S37,U14,
the inhibiting rates were over 40%. Oxymatrine at dose of
375mg/kg*10d, the life span prolongating rate against EAC
was 128.9%.
Indications:It
could be used for treatment of colon, esophageal, cervical,
cyst cancers and malignant lymphoma.
Composite prescription of the herb used
for treatment of colon cancer.
Radix Sophorae Flauescentis 15g
Caulis Sargentodoxae 15g
Fructus Akebiae 15g
Radix Saluiae Miltiorrhizae 15g
Herba Pteridis Multifidae 15g
Herba Hedyotis Diffusae 30g
Rhizoma Smilacis Chinensis 30g
Caulis Vitis Quinquangularis 30g
Semen Coicis 30g
Herba Solani 30g
Semen Trichosanthis 30g
Rhizoma Dryopteris 30g
Crassirhizomae Preparata 9g
Eupolyphaga seu Steleophaga
Herba Scutellariae Barbatae 30g
Fructus Mume 9g
Radix Aucklandiae 9g
Gekko Swinhoana (seu Chinensis) 4.5g
The herbs were boiled, administered orally,
one dose/daily, 50 cases of advanced colon cancer in which
15 cases have metastasis. The results showed that the surviving
rates of 1,2,3,4,5 years were 80%, 43.5%, 31.7%, 20% and 9.1%,
respectively.
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