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Sources:
The rhizoma of
Curcuma longa L. Family Zingiberacae.
Constituents:
Conaining curcumin, volatile oils, tumerone, zingiberene,
etc.
Actions:Studies
in vitro showed that the tumeric extract at a concentration
of 0.4mg/ml and curcumin 4ug/ml had cytotoxic effect to Dalton's
lymphom- a.Studies in vivo indicated that mice were given
1000000 dalton's lympho- ma cells intraperitoneally, tumeric
extract 40mg/mouse and curcumin lipos- omes 5mg/mouse were
given to the mice through the same route continu- ed for 10
days. The results showed that both turmeric extract and curcumin
had a significant reduction of the death rate and tumor formation
in mice, the tumor formation rates were 12% and 40%, survived
rates after 60 days were 50% and 60% in tumeric extract group
and curcumin group respect iv- ely, but the tumor formation
rate was 100% and the survival rate after 60 days was 0% in
the control group. An other experiment proved that topical
application of 1, 3 or TPA twice weekly for 20 weeks to mice
previously tre- at with DMBA, could inhibit the TPA induced
tumors per mouse.The inhibi- ting rates were 39%, 77% and
98% respectively.
Indications:
(1) Composite prescription for analgesic
effect on primary hepatoma:
Radix et Rhizoma Rhei 50g
Cortex Phellodendri 50g
Rhizoma curcumae Longae 50g
Natrii sulfas 50g
Folium Hibisci Mutabilis 50g
Borneolum Syntheticum 20g
Rhizoma Arisaematis 20g
Olibanum 20g
Myrrha 20g
Realgar 30g
Radix Txichosanthis 100g
The above herbs were ground into powder
and mixed with starch and finally made into paste for external
application to the cancer lesion. The prescription was used
to treat 31 cases , 24 cases remarkably improved, remarkable
rate of 72.4%. 7 cases improved, the effective rate of 22.6%.
(2) 0.5% ointment of curcumin topical
application 3 times a day found to have remarkable symptomatic
relief in 62 patients with external cancerous lesions. The
results showed: reduction in smell was noted in 90% of the
cases and reduction of itching in almost all cases, reduction
of pain was observed in 50% cases . The exudate of lesions
decreased in 70% of the cases, and the size of lesions was
reduced in 10% patients.
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